Gamma-Aminobutyric Acid with Vitamin B-6 (key precursor)

• Inhibitory neurotransmitter (reduces nervous tension)

• Main neurotransmitter of the Central Nervous System

• Anxiolytic, calming, and sedative effect. Non-addictive

Gamma-Aminobutyric Acid (IUPAC: 4-aminobutanoic acid), also known as GABA, is a four-carbon amino acid with the amino group located at the end of the carbon chain. It is the primary inhibitory neurotransmitter in the Central Nervous System (CNS) of mammals. GABA plays a crucial role in regulating neuronal excitability throughout the nervous system.

It acts as a key neurotransmitter, binding to specific receptors and inducing synaptic inhibition, leading to sedation.

Neuronal cells have specific receptors for GABA. When GABA binds to these receptors, it opens a channel that allows chloride ions to enter the neuron, causing hyperpolarization. This makes it harder for the neuron to depolarize, reducing neuronal conduction and inhibiting the CNS.

GABA is classified as an inhibitory neurotransmitter because it decreases nerve tension by reducing action potentials in neurons. It produces anxiolytic, calming, and sedative effects similar to those of barbiturates and benzodiazepines. Unlike these drugs, however, GABA does not cause dependence or have reported side effects and contraindications. Anxiety and nervousness result from excessive neuronal firing. GABA crosses the synapses and binds to GABA receptors on the next neuron, opening chloride channels, hyperpolarizing the neuron and preventing further action potentials. The result is reduced anxiety, nervousness, and improved sleep onset.

GABA is found in its levorotatory form (L-GABA), which is the natural form present in the human body.

GABA is also a precursor of Acetylcholine, which plays a vital role in the secretion of growth hormone. GABA acts by inhibiting the production of somatostatin in the hypothalamus, thereby increasing the release of growth hormone. This formula is also enriched with Vitamin B6. Vitamin B6 is essential for GABA synthesis by activating the enzyme GABA-T (GABA transferase), facilitates GABA’s passage through the blood-brain barrier, and is responsible for the conversion of 5-HTP into Serotonin.

Ingredients
Other ingredients: Hypromellose (cellulose capsule), ascorbyl palmitate, stearic acid (vegetable source), and silicon dioxide.

Composition
Per 1 capsule:
GABA (Gamma-Aminobutyric Acid) – 750 mg

Directions for Use
Take 1 capsule 1 to 2 times a day as needed, preferably with juice or water on an empty stomach.

Warnings
For adults only. Consult a physician if pregnant or breastfeeding, taking medication, or if you have a medical condition. Keep out of reach of children. Store in a cool, dry place after opening.